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The Centers for Disease Control and Prevention (CDC) stated in 2009: "Studies indicate that oral sex is commonly practiced by sexually active male-female and same-gender couples of various ages, including adolescents." Any sexual exchange of bodily fluids with a person infected with HIV, the virus that causes AIDS, poses a risk of infection.

Risk of STI infection, however, is generally considered significantly lower for oral sex than for vaginal or anal sex, with HIV transmission considered the lowest risk with regard to oral sex.

For conception to take place, sperm from the penis must enter the uterus and fallopian tubes and fertilize the female's egg.

In humans, there is no connection between the gastrointestinal system and the reproductive system, and sperm ingested by the woman would be killed and broken down by acids in her stomach and proteins in the small intestine.

The report comes from the results of a computer-administered survey of over 12,000 Americans between the ages of 15 and 44, and states that over half the teenagers questioned have had oral sex.

While any exposure to a partner's semen appears to decrease a woman's chances for the various immunological disorders that can occur during pregnancy, immunological tolerance could be most quickly established through the oral introduction and gastrointestinal absorption of semen.

An act of group sex restricted to one woman giving oral sex to several men is referred to as a gangsuck, blowbang or lineup, all derivatives of the slang term gang bang for group sex. Oral sex is commonly used as a means of preserving virginity, especially among heterosexual pairings; this is sometimes termed technical virginity (which additionally includes anal sex, mutual masturbation and other non-penetrative sex acts, but excludes penile-vaginal sex).

Additionally, gay males may regard oral sex as a way of maintaining their virginities, with penile-anal penetration defined as resulting in virginity loss, while other gay males may define oral sex as their main form of sexual activity.

Oral sex is not necessarily an effective method of preventing sexually transmitted infections (STIs), although some forms of STIs are believed to be less commonly spread in this way, and oral sex has been recommended as a form of safe sex.

but using a real dental dam is seen as preferable; this is because real dental dams cover a larger area, avoid accidents caused by "slipping" outside the covered area, and avoid the risk that makeshift versions may be accidentally damaged or poked with the scissors during the cutting procedure.

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